Excessive daytime sleepiness is common in many conditions, including narcolepsy. A number of stimulant medications are used to treat this condition, but they can have side effects such as dependence and heart problems.
A new smart pill called modafinil has been developed to promote wakefulness and decrease daytime sleepiness. The smart pill works differently from the other stimulants used to treat narcolepsy, though it may be more effective than Armodafinil.
Stimulants and Wakefulness-Promoting Smart Pill
Modafinil is a medication used to treat sleepiness caused by narcolepsy, obstructive sleep apnea (OSA), and shift work disorder (SWD). Modvigil 200 Australia is also used as a stimulant by people who want to improve their alertness and concentration. It is available as a tablet that must be taken by mouth, usually once a day.
It is a type of central nervous system stimulant, but it differs from amphetamine in that it has less effect on arousal. Buy Artvigil Australia works to increase wakefulness in patients with sleep disorders by affecting areas in the brain that control wakefulness and attention.
Awakening Mechanism
The most common form of wakefulness-promoting effect is on the prefrontal cortex, which is located in the front part of the brain. Its effects on this area are believed to be mediated by the activation of post-synaptic adrenergic receptors. It may also affect the release of adenosine from acetylcholine receptors in the prefrontal cortex, and the production of epinephrine from adrenergic receptors in the lungs.
However, It has been found to have an even greater effect on the perifornical area of the brain than on the prefrontal cortex. In this area, it has been shown to activate Fos-immunoreactive cells of the orexin (hypocretin) system.
Orexin is a neurochemical that is deficient in people with narcolepsy. Narcoleptics who are deficient in orexin have more severe and prolonged sleepiness, compared to those who do not. In animal models, armodafinil stimulates wakefulness in orexin-deficient animals, but not in wild-type mice. This indicates that narcoleptics have more orexin-related sleepiness than other people do, and it suggests that modafinil may be a useful therapy for narcoleptics who are deficient in this neurochemical.
Unlike amphetamine, modafinil has few or no side effects when used at the recommended dose. It has also been found to be highly effective in narcoleptics, and it has a relatively low risk of abuse or addiction.
It can be taken by mouth once a day with or without food. It is best to take it at the same time each day, and it should not be taken more often than prescribed by your doctor.
In some cases, modafinil can cause a serious skin rash, including erythema multiforme major (EMM) and Stevens-Johnson syndrome. If these rashes occur, stop taking the medication and call your doctor right away.
Other side effects of armodafinil may include drowsiness, increased heart rate, or dizziness. These side effects usually go away after you stop taking the smart pill. If they do not, ask your doctor about other ways to reduce the symptoms.
You must also talk to your doctor about how much armodafinil you need each day. You may need to take it for a long time, and you should not use it in place of other treatments for your sleep disorder.
This medicine can be habit-forming, so you must not take it more than prescribed. Taking it too often can make you more sleepy, and it may not work as well.
Before you start taking this medicine, tell your doctor if you have any of these conditions: Alzheimer’s disease; angina; a history of depression or other mental illness; heart problems; high blood pressure; or kidney disease. You should also tell your doctor if you are using any other medicines, vitamins, or herbal products.